(Because yes, Marvel are apparently doing that already, and they've decided Jeph Loeb is the guy to do it, and for all that I hate to contribute to the general aura of pessimism in the western comic fan community over every new development that gets announced, with the state of Loeb's work in recent years it is beyond me to picture this ending well.)
Ahem.
Well, it goes without saying that it would be a Cable & Deadpool series, doesn't it? Only that's not something that would be so easy to justify now, looking at the direction either character has been taken in since their big break-up. Not impossible, but short of ignoring everything that's been done with either of them since their break-up (tempting, but not exactly clever) you'd have to think carefully about what direction you'd approach it from in order to make it work.
( Here's how my version would go. )
Ahem.
Well, it goes without saying that it would be a Cable & Deadpool series, doesn't it? Only that's not something that would be so easy to justify now, looking at the direction either character has been taken in since their big break-up. Not impossible, but short of ignoring everything that's been done with either of them since their break-up (tempting, but not exactly clever) you'd have to think carefully about what direction you'd approach it from in order to make it work.
( Here's how my version would go. )